Akaki Kalmakhelidze graduated from the Institute of Public Affairs of Georgia in 2002 where he was awarded the MA degree in Public Administration. In 1994-1998 he studied at Ivane Javakhishvili State University on the Faculty of International Relations.
In 1998- 2000 Akaki worked at Public Defender's Office of Georgia. In 2001, he passed four-month training at the Legal Issues Department of the Council of Europe. In 2002 he started working at NGO Georgia in NATO as a coordinator of the program and headed the organization from 2004 to 2011. In 2012-2014 he held the position of the director at Anaklia Development LLC.
From 2012, he worked at the construction company Anagi at the same time, where he participated in developing tender proposals of the trading center East Point and Tbilisi Gardens. Since 2015 Akaki holds the position of Digital Marketing Manager at Anagi.